(1) | 12.1y/w/a | | Jill Hall | (Mitcham AC) | SEMIS | Croydon Arena | 20 May 1961 |
| 12.1w/+4.5 | CBP | Lynne Draper | (Redhill & Reigate AC) | 1 FINAL | Motspur Park | 16 May 1981 |
(3) | 12.2y | CBP | Madeleine Weston | (Selsonia Ladies AC) | 1 FINAL | Croydon Arena | 28 May 1955 |
(4) | 12.3y/w/a | | Jill Hall | (Mitcham AC) | 1 FINAL | Croydon Arena | 20 May 1961 |
| 12.3y | | Janet Stroud | (Fleetwood CSS, Chessington) | 1 FINAL | Wimbledon Park | 13 May 1967 |
(6) | 12.35/+0.3 | | Shivelle Marshall | (Croydon Harriers) | 1 FINAL | Kingsmeadow Stadium | 12 May 2024 |
(7) | 12.4y/w/a | | D Fowler | (Hercules AC) | 2 FINAL | Croydon Arena | 20 May 1961 |
| 12.4w/+4.5 | | Jackie Harman | (unattached) | 2 FINAL | Motspur Park | 16 May 1981 |
| 12.4w/+2.6 | | Donna Fraser | (Croydon Harriers) | 1 FINAL | Tooting Bec | 17 May 1987 |
| 12.40/-1.1 | | Charmont Webster-Tape | (Sutton & District AC) | 1 FINAL | Kingsmeadow Stadium | 25 May 2014 |
| 12.40/-1.2 | | Isabella Akpoveta | (Crawley AC) | 1 FINAL | Kingsmeadow Stadium | 14 May 2023 |
(12) | 12.41/+0.3 | | Pyale Wifa | (Herne Hill Harriers) | 2 FINAL | Kingsmeadow Stadium | 12 May 2024 |
(13) | 12.43/+0.5 | | Aaliyah Brown | (South London Harriers) | 1 FINAL | Kingsmeadow Stadium | 12 May 2019 |
(14) | 12.48 | | Zipporah Golding | (Hercules Wimbledon AC) | 1 FINAL | Kingsmeadow Stadium | 14 May 2017 |
| 12.48/-0.5 | | Toni Bryan | (Croydon Harriers) | 1 S-FINAL 1 | Kingsmeadow Stadium | 14 May 2017 |
(16) | 12.5y | | Eileen Glazebrook | (Hercules AC) | 1 FINAL | Croydon Arena | 15 May 1954 |
| 12.5y/w/a | | C Howard | (Mitcham AC) | 3 FINAL | Croydon Arena | 20 May 1961 |
| 12.5y/w/a | | Celia Biggs | (Royal Borough of Kingston AC) | 4 FINAL | Croydon Arena | 20 May 1961 |
| 12.5y | | Sue Knight | (Mitcham AC) | 2 FINAL | Wimbledon Park | 13 May 1967 |
| 12.5 | | Rosemary Leech | (Mitcham AC) | HEATS | Wimbledon Park | 31 May 1969 |
| 12.50/-0.3 | | Arabella Wilson | (Winchester & District AC) | 1 FINAL | Kingsmeadow Stadium | 1 August 2021 |
(22) | 12.51/+1.6 | | Dominique Blaize | (Kingston AC & Polytechnic Harriers) | 1 FINAL | Kingsmeadow Stadium | 12 May 2002 |
(23) | 12.52/+1.5 | | Twinelle Hopeson | (Archbishop Tennison School, Croydon) | 1 FINAL | Kingsmeadow Stadium | 14 May 2006 |
| 12.52/-1.1 | | Natasha Alfred | (Herne Hill Harriers) | 2 FINAL | Kingsmeadow Stadium | 25 May 2014 |
| 12.52/-2.2 | | Lakeisha Owusu-Junior | (Herne Hill Harriers) | 1 FINAL | Kingsmeadow Stadium | 24 May 2015 |
|
25 performances of 12.52 or better. |